Failure of Immunotherapy—The Molecular and Immunological Origin of Immunotherapy Resistance in Lung Cancer

Failure of Immunotherapy—The Molecular and Immunological Origin of Immunotherapy Resistance in Lung Cancer

Immune checkpoint inhibitors (ICIs) have a huge impact on clinical treatment results in non-small cell lung cancer (NSCLC). Blocking antibodies targeting programmed cell death protein 1 (PD-1), programmed cell death protein ligand 1 (PD-L1) or CTLA-4 (cytotoxic T cell antigen 4) have been developed...

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Bibliographic Details
Main Authors: Justyna Błach, Kamila Wojas-Krawczyk, Marcin Nicoś, Paweł Krawczyk
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
immunotherapy
tumor resistance
immune checkpoint inhibitors
lung cancer
tumor immune escape
Online Access:https://www.mdpi.com/1422-0067/22/16/9030

Internet

https://www.mdpi.com/1422-0067/22/16/9030

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