A gene module identification algorithm and its applications to identify gene modules and key genes of hepatocellular carcinoma
Abstract To further improve the effect of gene modules identification, combining the Newman algorithm in community detection and K-means algorithm framework, a new method of gene module identification, GCNA-Kpca algorithm, was proposed. The core idea of the algorithm was to build a gene co-expressio...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-84837-y |