Viremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and function.

Viremic HIV infected individuals with high CD4 T cells and functional envelope proteins show anti-gp41 antibodies with unique specificity and function.

BACKGROUND: CD4 T-cell decay is variable among HIV-infected individuals. In exceptional cases, CD4 T-cell counts remain stable despite high plasma viremia. HIV envelope glycoprotein (Env) properties, namely tropism, fusion or the ability to induce the NK ligand NKp44L, or host factors that modulate...

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Bibliographic Details
Main Authors: Marta Curriu, Hughes Fausther-Bovendo, María Pernas, Marta Massanella, Jorge Carrillo, Cecilia Cabrera, Cecilio López-Galíndez, Bonaventura Clotet, Patrice Debré, Vincent Vieillard, Julià Blanco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3270019?pdf=render

Internet

http://europepmc.org/articles/PMC3270019?pdf=render

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