Host predisposition by endogenous Transforming Growth Factor-β1 overexpression promotes pulmonary fibrosis following bleomycin injury

<p>Abstract</p> <p>Background</p> <p>Idiopathic Pulmonary Fibrosis (IPF) is a progressive diffuse disease involving the lung parenchyma. Despite recent advances, the molecular mechanisms of the initiation and progression of this disease remain elusive. Previous studies...

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Bibliographic Details
Main Authors: Ferguson Mark WJ, Martin Gail, Tomlinson Annette, Birch Mary, Keating Dominic T, Malizia Andrea P, Haider Yussef, Doran Peter P, Egan Jim J
Format: Article
Language:English
Published: BMC 2007-09-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/4/1/18