Dexmedetomidine Oral Mucosa Patch for Sedation Suppresses Apoptosis in Hippocampus of Normal Rats

Dexmedetomidine Oral Mucosa Patch for Sedation Suppresses Apoptosis in Hippocampus of Normal Rats

Purpose Dexmedetomidine, an α2-adrenergic agonist, provides sedative and analgesic effects without significant respiratory depression. Dexmedetomidine has been suggested to have an antiapoptotic effect in response to various brain insults. We developed an oral mucosa patch using dexmedetomidine for...

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Bibliographic Details
Main Authors: Je Hoon Park, Il Gyu Ko, Sung Eun Kim, Jun Jang Jin, Lakkyong Hwang, Chang Ju Kim, Soo Hwan Yoon, Jongki Hong, Jun Young Chung, Deok Won Lee
Format: Article
Language:English
Published: Korean Continence Society 2017-04-01
Series:International Neurourology Journal
Subjects:
Dexmedetomidine
Apoptosis
Cell proliferation
Hippocampus
Rats
Online Access:http://www.einj.org/upload/pdf/inj-1734884-442.pdf

Internet

http://www.einj.org/upload/pdf/inj-1734884-442.pdf

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