PPE Surface Proteins Are Required for Heme Utilization by Mycobacterium tuberculosis
Iron is essential for replication of Mycobacterium tuberculosis, but iron is efficiently sequestered in the human host during infection. Heme constitutes the largest iron reservoir in the human body and is utilized by many bacterial pathogens as an iron source. While heme acquisition is well studied...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-01-01
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Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/8/1/e01720-16 |