Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models

Background. For development of individualized treatment on a routine basis, transfer of patients’ tumor tissue in a xenograft model (i.e., generation of patient-derived xenografts (PDX)) is desirable for molecular, biochemical, or functional analyses. Drawbacks are dissatisfactory tumor take rates,...

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Bibliographic Details
Main Authors: Michael Gock, Florian Kühn, Christina Susanne Mullins, Mathias Krohn, Friedrich Prall, Ernst Klar, Michael Linnebacher
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/1715053