Regulation of toll-like receptor signaling by the SF3a mRNA splicing complex.

The innate immune response plays a key role in fighting infection by activating inflammation and stimulating the adaptive immune response. However, chronic activation of innate immunity can contribute to the pathogenesis of many diseases with an inflammatory component. Thus, various negatively actin...

Full description

Bibliographic Details
Main Authors: Brian P O'Connor, Thomas Danhorn, Lesly De Arras, Brenna R Flatley, Roland A Marcus, Eveline Farias-Hesson, Sonia M Leach, Scott Alper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4450051?pdf=render