Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from <i>Psychrobacter</i> Sp. B6

Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from <i>Psychrobacter</i> Sp. B6

Aromatic amino acid aminotransferases present a special potential in the production of drugs and synthons, thanks to their ability to accommodate a wider range of substrates in their active site, in contrast to aliphatic amino acid aminotransferases. The mechanism of active site adjustment toward su...

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Bibliographic Details
Main Authors: Anna Bujacz, Jedrzej Rum, Maria Rutkiewicz, Agnieszka J. Pietrzyk-Brzezinska, Grzegorz Bujacz
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Materials
Subjects:
crystal structure
aromatic amino acids aminotransferase
active center adaptability
substrate specificity
psychrophilic
enzyme-inhibitor complexes
Online Access:https://www.mdpi.com/1996-1944/14/12/3351

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https://www.mdpi.com/1996-1944/14/12/3351

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