Pentapeptides derived from Aβ1–42 protect neurons from the modulatory effect of Aβ fibrils—an in vitro and in vivo electrophysiological study

Short fragments and fragment analogues of beta-amyloid 1–42 peptide (Aβ1–42) display a protective effect against Aβ-mediated neurotoxicity. After consideration of our earlier results with in vitro bioassay of synthetic Aβ-recognition peptides and toxic fibrillar amyloids, five pentapeptides were sel...

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Bibliographic Details
Main Authors:	V. Szegedi, L. Fülöp, T. Farkas, E. Rózsa, H. Robotka, Z. Kis, Z. Penke, S. Horváth, Z. Molnár, Z. Datki, K. Soós, J. Toldi, D. Budai, M. Zarándi, B. Penke
Format:	Article
Language:	English
Published:	Elsevier 2005-04-01
Series:	Neurobiology of Disease
Subjects:	Alzheimer's disease β-amyloid 1–42 Neuroprotective pentapeptides Electrophysiology Microiontophoresis Single-unit activity
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996104003183

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http://www.sciencedirect.com/science/article/pii/S0969996104003183

Pentapeptides derived from Aβ1–42 protect neurons from the modulatory effect of Aβ fibrils—an in vitro and in vivo electrophysiological study

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