The force-temperature relationship in healthy and dystrophic mouse diaphragm; implications for translational study design.

In the field of muscular dystrophy, striated muscle function is often assessed in vitro in dystrophin-deficient mdx mice in order to test the impact of a potential treatment strategy. Although many past studies have assessed diaphragm contractile function at or near room temperature, the diaphragm...

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Bibliographic Details
Main Authors: Jason D Murray, Ben D Canan, Christopher D Martin, Jenna E Stangland, Neha eRastogi, Jill A Rafael-Fortney, Paul M. L. Janssen
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Physiology
Subjects:
mdx
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00422/full