Lysosome and proteasome dysfunction in alcohol-induced liver injury

The review describes research findings on the influence of alcohol consumption on two crucial catabolic systems in hepatocytes: the lysosome and the ubiquitin-proteasome system (UPS). The lysosome is a membrane-bound organelle that degrades all aging and/or damaged organelles and hydrolyzes all form...

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Bibliographic Details
Main Authors: Terrence M. Donohue, Jr., Natalia A. Osna, Kusum K. Kharbanda, Paul G. Thomes
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-12-01
Series:Liver Research
Online Access:http://www.sciencedirect.com/science/article/pii/S254256841930039X