Neurotrophins induce fission of mitochondria along embryonic sensory axons

Neurotrophins are growth factors that have a multitude of roles in the nervous system. We report that neurotrophins induce the fission of mitochondria along embryonic chick sensory axons driven by combined PI3K and Mek-Erk signaling. Following an initial burst of fission, a new steady state of neuro...

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Bibliographic Details
Main Authors: Lorena Armijo-Weingart, Andrea Ketschek, Rajiv Sainath, Almudena Pacheco, George M Smith, Gianluca Gallo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
ngf
Online Access:https://elifesciences.org/articles/49494