Depressed nNOS expression during spine transition in the developing hippocampus of FMR1 KO mice

Nitric oxide (NO), synthesized as needed by NO synthase (NOS), is involved in spinogenesis and synaptogenesis. Immature spine morphology is characteristic of fragile X syndrome (FXS). The objective of this research was to investigate and compare changes of postnatal neuronal NOS (nNOS) expression in...

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Bibliographic Details
Main Authors: Qin Xu, Zhiwei Zhu, Jialu Xu, Weizhong Gu, Zhengyan Zhao
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
FXS
NO
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200017&lng=en&tlng=en