A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma

A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma

Background: Malignant pleural mesothelioma (MPM) is an aggressive cancer related to asbestos exposure. Early diagnosis is challenging due to generic symptoms and a lack of biomarkers. We previously demonstrated that mesothelial precursor cells (MPC) characterized by mesothelin (MSLN)+CD90+CD34+ coul...

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Bibliographic Details
Main Authors: Bill T.V. Duong, Licun Wu, Brenda J. Green, Fatemeh Bavaghar-Zaeimi, Zongjie Wang, Mahmoud Labib, Yuxiao Zhou, Fernando J.P. Cantu, Thurgaa Jeganathan, Sandra Popescu, Jennifer Pantea, Marc de Perrot, Shana O. Kelley
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:EBioMedicine
Subjects:
Mesothelioma
Liquid biopsy
Mesothelial precursor cells
Diagnostic biomarker
Clinical prognosis
Molecular profiling
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420304072

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http://www.sciencedirect.com/science/article/pii/S2352396420304072

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