Non-associative potentiation of perisomatic inhibition alters the temporal coding of neocortical layer 5 pyramidal neurons.

In the neocortex, the coexistence of temporally locked excitation and inhibition governs complex network activity underlying cognitive functions, and is believed to be altered in several brain diseases. Here we show that this equilibrium can be unlocked by increased activity of layer 5 pyramidal neu...

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Bibliographic Details
Main Authors: Joana Lourenço, Simone Pacioni, Nelson Rebola, Geeske M van Woerden, Silvia Marinelli, David DiGregorio, Alberto Bacci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4086817?pdf=render