HP1β carries an acidic linker domain and requires H3K9me3 for phase separation

Liquid-liquid phase separation (LLPS) mediated formation of membraneless organelles has been proposed to coordinate biological processes in space and time. Previously, the formation of phase-separated droplets was described as a unique property of HP1α. Here, we demonstrate that the positive net cha...

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Bibliographic Details
Main Authors: Weihua Qin, Andreas Stengl, Enes Ugur, Susanne Leidescher, Joel Ryan, M. Cristina Cardoso, Heinrich Leonhardt
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Nucleus
Subjects:
Online Access:http://dx.doi.org/10.1080/19491034.2021.1889858