HIV-1 tolerates changes in A-count in a small segment of the pol gene
Abstract Background The HIV-1 RNA genome has a biased nucleotide composition with a surplus of As. Several hypotheses have been put forward to explain this striking phenomenon, but the A-count of the HIV-1 genome has thus far not been systematically manipulated. The reason for this reservation is th...
Main Authors: | Bep Klaver, Yme van der Velden, Formijn van Hemert, Antoinette C. van der Kuyl, Ben Berkhout |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-09-01
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Series: | Retrovirology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12977-017-0367-0 |
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