Systemic transplantation of adult multipotent stem cells prevents articular cartilage degeneration in a mouse model of accelerated ageing
Abstract Background Osteoarthritis (OA) is one of the most prevalent joint diseases of advanced age and is a leading cause of disability worldwide. Ageing is a major risk factor for the articular cartilage (AC) degeneration that leads to OA, and the age-related decline in regenerative capacity accel...
Main Authors: | Seth D. Thompson, Rajeswari Pichika, Richard L. Lieber, Mitra Lavasani |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Immunity & Ageing |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12979-021-00239-8 |
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