Systemic transplantation of adult multipotent stem cells prevents articular cartilage degeneration in a mouse model of accelerated ageing

Systemic transplantation of adult multipotent stem cells prevents articular cartilage degeneration in a mouse model of accelerated ageing

Abstract Background Osteoarthritis (OA) is one of the most prevalent joint diseases of advanced age and is a leading cause of disability worldwide. Ageing is a major risk factor for the articular cartilage (AC) degeneration that leads to OA, and the age-related decline in regenerative capacity accel...

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Bibliographic Details
Main Authors: Seth D. Thompson, Rajeswari Pichika, Richard L. Lieber, Mitra Lavasani
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Immunity & Ageing
Subjects:
Progeria
Accelerated ageing
Articular cartilage
Adult stem cells
Transplantation
Regenerative medicine
Online Access:https://doi.org/10.1186/s12979-021-00239-8

Internet

https://doi.org/10.1186/s12979-021-00239-8

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