Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors
Drug resistance invariably limits the response of oncogene-addicted cancer cells to targeted therapy. The upregulation of signal transducer and activator of transcription 3 (STAT3) has been implicated as a mechanism of drug resistance in a range of oncogene-addicted cancers. However, the development...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221323171830908X |