MDM2 Overexpression Modulates the Angiogenesis-Related Gene Expression Profile of Prostate Cancer Cells

MDM2 Overexpression Modulates the Angiogenesis-Related Gene Expression Profile of Prostate Cancer Cells

The Murine Double Minute 2 (MDM2) amplification or overexpression has been found in many tumors with high metastatic and angiogenic ability. Our experiments were designed to explore the impact of MDM2 overexpression, specifically on the levels of angiogenesis-related genes, which can also play a maj...

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Bibliographic Details
Main Authors: Thiagarajan Venkatesan, Ali Alaseem, Aiyavu Chinnaiyan, Sivanesan Dhandayuthapani, Thanigaivelan Kanagasabai, Khalid Alhazzani, Priya Dondapati, Saad Alobid, Umamaheswari Natarajan, Ruben Schwartz, Appu Rathinavelu
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Cells
Subjects:
MDM2
THBS1
MMP9
Angiogenesis
LNCaP-MST
PCR array
Nutlin-3
Online Access:http://www.mdpi.com/2073-4409/7/5/41

Internet

http://www.mdpi.com/2073-4409/7/5/41

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