Superior Expansion and Cytotoxicity of Human Primary NK and CAR-NK Cells from Various Sources via Enriched Metabolic Pathways

Superior Expansion and Cytotoxicity of Human Primary NK and CAR-NK Cells from Various Sources via Enriched Metabolic Pathways

Clinical success of chimeric antigen receptor (CAR) T cell immunotherapy requires the engineering of autologous T cells, which limits the broader implementation of CAR cell therapy. The development of allogeneic and universal cell products will significantly broaden their application and reduce cost...

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Bibliographic Details
Main Authors: Yan Yang, Saiaditya Badeti, Hsiang-chi Tseng, Minh Tuyet Ma, Ting Liu, Jie-Gen Jiang, Chen Liu, Dongfang Liu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
NK
CAR
expansion
CAR-NK
cytotoxicity
CD19-CAR-NK
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120301388

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http://www.sciencedirect.com/science/article/pii/S2329050120301388

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