Synergistic effects of TOR and proteasome pathways on the yeast transcriptome and cell growth

The proteasome has been implicated in gene transcription through a variety of mechanisms. How the proteasome regulates genome-wide transcription in relation to nutrient signalling pathways is largely unknown. Using chemical inhibitors to compromise the functions of the proteasome and/or TORC1, we re...

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Bibliographic Details
Main Authors: Nianshu Zhang, Zhenzhen Quan, Bharat Rash, Stephen G. Oliver
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120137