Myeloid mineralocorticoid receptor deficiency inhibits aortic constriction-induced cardiac hypertrophy in mice.

Myeloid mineralocorticoid receptor deficiency inhibits aortic constriction-induced cardiac hypertrophy in mice.

Mineralocorticoid receptor (MR) blockade has been shown to suppress cardiac hypertrophy and remodeling in animal models of pressure overload (POL). This study aims to determine whether MR deficiency in myeloid cells modulates aortic constriction-induced cardiovascular injuries. Myeloid MR knockout (...

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Bibliographic Details
Main Authors: Chao Li, Yu Yao Zhang, Ryan A Frieler, Xiao Jun Zheng, Wu Chang Zhang, Xue Nan Sun, Qing Zhen Yang, Shu Min Ma, Baozhuan Huang, Stefan Berger, Wang Wang, Yong Wu, Ying Yu, Sheng Zhong Duan, Richard M Mortensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4212990?pdf=render

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http://europepmc.org/articles/PMC4212990?pdf=render

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