Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival.
Chlamydiae replicate intracellularly in a vacuole called an inclusion. Chlamydial-infected host cells are protected from mitochondrion-dependent apoptosis, partly due to degradation of BH3-only proteins. The host-cell adapter protein 14-3-3beta can interact with host-cell apoptotic signaling pathway...
| Format: | Article |
|---|---|
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-05-01
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| Series: | PLoS Pathogens |
| Online Access: | http://dx.doi.org/10.1371/journal.ppat.0020045 |