GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data

GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data

Abstract Background B cell affinity maturation enables B cells to generate high-affinity antibodies. This process involves somatic hypermutation of B cell immunoglobulin receptor (BCR) genes and selection by their ability to bind antigens. Lineage trees are used to describe this microevolution of B...

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Bibliographic Details
Main Authors: Xingyu Yang, Christopher M. Tipton, Matthew C. Woodruff, Enlu Zhou, F. Eun-Hyung Lee, Inãki Sanz, Peng Qiu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Genomics
Subjects:
B cell receptor gene
Lineage tree
Online Access:http://link.springer.com/article/10.1186/s12864-020-06936-w

Internet

http://link.springer.com/article/10.1186/s12864-020-06936-w

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