Composite survival index to compare virulence changes in azole-resistant Aspergillus fumigatus clinical isolates.

Composite survival index to compare virulence changes in azole-resistant Aspergillus fumigatus clinical isolates.

Understanding resistance to antifungal agents in Aspergillus fumigatus is of increasing importance for the treatment of invasive infections in immunocompromised patients. Although a number of molecular resistance mechanisms are described in detail, the potential accompanying virulence changes and im...

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Bibliographic Details
Main Authors: Eleftheria Mavridou, Joseph Meletiadis, Pavol Jancura, Saiden Abbas, Maiken C Arendrup, Willem J G Melchers, Tom Heskes, Johan W Mouton, Paul E Verweij
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3753310?pdf=render

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http://europepmc.org/articles/PMC3753310?pdf=render

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