A Euploid Line of Human Embryonic Stem Cells Derived from a 43,XX,dup(9q),+12,-14,-15,-18,-21 Embryo.

Aneuploid embryos diagnosed by FISH-based preimplantation genetic screening (PGS) have been shown to yield euploid lines of human embryonic stem cells (hESCs) with a relatively high frequency. Given that the diagnostic procedure is usually based on the analysis of 1-2 blastomeres of 5 to 10-cell cle...

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Main Authors: Simone Aparecida Siqueira Fonseca, Roberta Montero Costas, Mariana Morato-Marques, Silvia Costa, Jose Roberto Alegretti, Carla Rosenberg, Eduardo Leme Alves da Motta, Paulo C Serafini, Lygia V Pereira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4634922?pdf=render