Extracellular redox sensitivity of Kv1.2 potassium channels

Abstract Kv1.2 is a prominent potassium channel subtype in the nervous system and serves as an important structural template for investigation of ion channel function. However, Kv1.2 voltage-dependence exhibits dramatic cell-to-cell variability due to a gating mode shift that is regulated by an unkn...

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Bibliographic Details
Main Authors: Victoria A. Baronas, Runying Y. Yang, Harley T. Kurata
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08718-z