The ‘R’ principles in laboratory animal experiments

Abstract Since the Three Rs of replacement, reduction and refinement was proposed by Russel and Birch in 1959, researchers have a moral duty to minimize harm to animals. Even though animal experiments are performed by the Three Rs concept, animal researches which do not comply with international rul...

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Bibliographic Details
Main Authors: Kook Hyun Lee, Dong Won Lee, Byeong Chul Kang
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Laboratory Animal Research
Subjects:
Online Access:https://doi.org/10.1186/s42826-020-00078-6