Evolutionary Dynamics of the SKN-1 → MED → END-1,3 Regulatory Gene Cascade in Caenorhabditis Endoderm Specification

Evolutionary Dynamics of the SKN-1 → MED → END-1,3 Regulatory Gene Cascade in Caenorhabditis Endoderm Specification

Gene regulatory networks and their evolution are important in the study of animal development. In the nematode, Caenorhabditis elegans, the endoderm (gut) is generated from a single embryonic precursor, E. Gut is specified by the maternal factor SKN-1, which activates the MED → END-1,3 → ELT-2,7 cas...

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Bibliographic Details
Main Author: Morris F. Maduro
Format: Article
Language:English
Published: Oxford University Press 2020-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
gata factors
cell fate specification
gene regulatory network
developmental system drift
caenorhabditis
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400724

Internet

http://g3journal.org/lookup/doi/10.1534/g3.119.400724

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