HIV-I Nef inhibitors: a novel class of HIV-specific immune adjuvants in support of a cure

Abstract The success of many current vaccines relies on a formulation that incorporates an immune activating adjuvant. This will hold true for the design of a successful therapeutic HIV vaccine targeted at controlling reactivated virus following cessation of combined antiretroviral therapy (cART). T...

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Bibliographic Details
Main Authors: Gregory A. Dekaban, Jimmy D. Dikeakos
Format: Article
Language:English
Published: BMC 2017-09-01
Series:AIDS Research and Therapy
Subjects:
Nef
Online Access:http://link.springer.com/article/10.1186/s12981-017-0175-6