Targeting of pseudorabies virus structural proteins to axons requires association of the viral Us9 protein with lipid rafts.
The pseudorabies virus (PRV) Us9 protein plays a central role in targeting viral capsids and glycoproteins to axons of dissociated sympathetic neurons. As a result, Us9 null mutants are defective in anterograde transmission of infection in vivo. However, it is unclear how Us9 promotes axonal sorting...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-05-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2361720?pdf=render |