CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopes.

CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopes.

CD8+ T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of information from viral and bacterial infections, little is known about the antigen specificity or the general...

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Bibliographic Details
Main Authors: Diana L Martin, D Brent Weatherly, Susana A Laucella, Melissa A Cabinian, Matthew T Crim, Susan Sullivan, Mark Heiges, Sarah H Craven, Charles S Rosenberg, Matthew H Collins, Alessandro Sette, Miriam Postan, Rick L Tarleton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1526708?pdf=render

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http://europepmc.org/articles/PMC1526708?pdf=render

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