Identifying activating mutations in the EGFR gene: prognostic and therapeutic implications in non-small cell lung cancer

Identifying activating mutations in the EGFR gene: prognostic and therapeutic implications in non-small cell lung cancer

AbstractLung cancer is the leading cause of cancer-related deaths worldwide. Promising new therapies have recently emerged from the development of molecular targeted drugs; particularly promising are those blocking the signal transduction machinery of cancer cells. One of the most widely studied cel...

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Bibliographic Details
Main Authors: Gabriel Lima Lopes, Edoardo Filippo de Queiroz Vattimo, Gilberto de Castro Junior
Format: Article
Language:English
Published: Sociedade Brasileira de Pneumologia e Tisiologia 2015-08-01
Series:Jornal Brasileiro de Pneumologia
Subjects:
Terapia de alvo molecular
Receptor do fator de crescimento epidérmico
Neoplasias pulmonares/quimioterapia
Mutação
Oncogenes
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132015000400365&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132015000400365&lng=en&tlng=en

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