Gene expression signature-based screening identifies new broadly effective influenza a antivirals.

Classical antiviral therapies target viral proteins and are consequently subject to resistance. To counteract this limitation, alternative strategies have been developed that target cellular factors. We hypothesized that such an approach could also be useful to identify broad-spectrum antivirals. Th...

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Bibliographic Details
Main Authors: Laurence Josset, Julien Textoris, Béatrice Loriod, Olivier Ferraris, Vincent Moules, Bruno Lina, Catherine N'guyen, Jean-Jacques Diaz, Manuel Rosa-Calatrava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20957181/?tool=EBI