Chemotherapy-induced late transgenerational effects in mice.

To our knowledge, there is no report on long-term reproductive and developmental side effects in the offspring of mothers treated with a widely used chemotherapeutic drug such as doxorubicin (DXR), and neither is there information on transmission of any detrimental effects to several filial generati...

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Bibliographic Details
Main Authors: Loro L Kujjo, Eun A Chang, Ricardo J G Pereira, Shilpa Dhar, Brenda Marrero-Rosado, Satyaki Sengupta, Hongbing Wang, Jose B Cibelli, Gloria I Perez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060098?pdf=render