4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion.

Toxoplasma gondii is a eukaryotic parasite of the phylum Apicomplexa that is able to infect a wide variety of host cells. During its active invasion process it secretes proteins from discrete secretory organelles: the micronemes, rhoptries and dense granules. Although a number of rhoptry proteins ha...

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Bibliographic Details
Main Authors: Sandeep Ravindran, Melissa B Lodoen, Steven H L Verhelst, Matthew Bogyo, John C Boothroyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2780294?pdf=render