Empirical evaluation of data normalization methods for molecular classification

Background Data artifacts due to variations in experimental handling are ubiquitous in microarray studies, and they can lead to biased and irreproducible findings. A popular approach to correct for such artifacts is through post hoc data adjustment such as data normalization. Statistical methods for...

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Bibliographic Details
Main Authors: Huei-Chung Huang, Li-Xuan Qin
Format: Article
Language:English
Published: PeerJ Inc. 2018-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/4584.pdf