Mixed Pluronic—Cremophor Polymeric Micelles as Nanocarriers for Poorly Soluble Antibiotics—The Influence on the Antibacterial Activity

Mixed Pluronic—Cremophor Polymeric Micelles as Nanocarriers for Poorly Soluble Antibiotics—The Influence on the Antibacterial Activity

In this work, novel polymeric mixed micelles from Pluronic F127 and Cremophor EL were investigated as drug delivery systems for Norfloxacin as model antibiotic drug. The optimal molar ratio of surfactants was determined, in order to decrease critical micellar concentration (CMC) and prepare carriers...

Full description

Bibliographic Details
Main Authors: Maria Antonia Tănase, Adina Raducan, Petruţa Oancea, Lia Mara Diţu, Miruna Stan, Cristian Petcu, Cristina Scomoroşcenco, Claudia Mihaela Ninciuleanu, Cristina Lavinia Nistor, Ludmila Otilia Cinteza
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceutics
Subjects:
mixed polymeric micelles
drug delivery
antibiotics
Pluronic F127
Online Access:https://www.mdpi.com/1999-4923/13/4/435

Internet

https://www.mdpi.com/1999-4923/13/4/435

Similar Items