Dysregulation of protein synthesis and dendritic spine morphogenesis in ASD: studies in human pluripotent stem cells

Abstract Autism spectrum disorder (ASD) is a brain disorder that involves changes in neuronal connections. Abnormal morphology of dendritic spines on postsynaptic neurons has been observed in ASD patients and transgenic mice that model different monogenetic causes of ASD. A number of ASD-associated...

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Bibliographic Details
Main Authors: Louisa Hoi-Ying Lo, Kwok-On Lai
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Autism
Online Access:http://link.springer.com/article/10.1186/s13229-020-00349-y