Dysregulation of protein synthesis and dendritic spine morphogenesis in ASD: studies in human pluripotent stem cells
Abstract Autism spectrum disorder (ASD) is a brain disorder that involves changes in neuronal connections. Abnormal morphology of dendritic spines on postsynaptic neurons has been observed in ASD patients and transgenic mice that model different monogenetic causes of ASD. A number of ASD-associated...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Molecular Autism |
Online Access: | http://link.springer.com/article/10.1186/s13229-020-00349-y |