Dendritic spines and pre-synaptic boutons are stable despite local deep hypothermic challenge and re-warming in vivo.

Deep hypothermia to 20°C is used clinically for major pediatric and adult surgical procedures. In particular, it is used in the "standstill operation" where blood flow is stopped for up to 30 min. Patients recovering from these procedures can exhibit neurological deficits. Such deficits co...

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Bibliographic Details
Main Authors: Yicheng Xie, Shangbin Chen, Timothy Murphy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3341353?pdf=render