Lack of dystrophin functionally affects α3β2/β4-nicotinic acethylcholine receptors in sympathetic neurons of dystrophic mdx mice

Lack of dystrophin functionally affects α3β2/β4-nicotinic acethylcholine receptors in sympathetic neurons of dystrophic mdx mice

In the sympathetic superior cervical ganglion (SCG), nicotinic acetylcholine receptors (nAChRs) mediate fast synaptic transmission. We previously demonstrated that in SCG neurons of mdx mice, an animal model for Duchenne muscular dystrophy, lack of dystrophin causes a decrease, compared to the wild-...

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Bibliographic Details
Main Authors: Silvia Di Angelantonio, Maria Egle De Stefano, Alessio Piccioni, Loredana Lombardi, Cecilia Gotti, Paola Paggi
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Neurobiology of Disease
Subjects:
Nicotinic acetylcholine receptors
Duchenne muscular dystrophy
Autonomic neurons
Western immunoblot
Immunohistochemistry
Patch-clamp recording
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110003670

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http://www.sciencedirect.com/science/article/pii/S0969996110003670

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