Heat-stress-modulated induction of NF-κB leads to brucellacidal pro-inflammatory defense against Brucella abortus infection in murine macrophages and in a mouse model

Heat-stress-modulated induction of NF-κB leads to brucellacidal pro-inflammatory defense against Brucella abortus infection in murine macrophages and in a mouse model

Abstract Background Brucella causes a chronic and debilitating infection that leads to great economic losses and a public health burden. In this study, we demonstrated the brucellacidal effect of heat shock mediated by the induction of pro-inflammatory cytokines, reactive oxygen species (ROS) accumu...

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Bibliographic Details
Main Authors: Huynh Tan Hop, Lauren Togonon Arayan, Alisha Wehdnesday Bernardo Reyes, Tran Xuan Ngoc Huy, Won Gi Min, Hu Jang Lee, Man Hee Rhee, Hong Hee Chang, Suk Kim
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Microbiology
Subjects:
B. abortus
Heat stress
Macrophage
NF-κB
ROS
Online Access:http://link.springer.com/article/10.1186/s12866-018-1185-9

Internet

http://link.springer.com/article/10.1186/s12866-018-1185-9

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