Synthesis and Antitumor Activity of (3-Hydroxyacrylato-O,O′) Diammineplatinum(II)

As an indispensable part of cancer chemotherapy, platinum drugs still play an important role in cancer treatment. In this study, two platinum(II) complexes with Michael acceptor 3-hydroxyacrylic acid as the leaving group were synthesized from cis-diamminediiodo platinum(II) and 3-ethoxyacrylic acid....

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Bibliographic Details
Main Authors: Yong-Zhi Shu, Jun Lin, Bao-Quan Zhu, Quan-Hai Liu, Bin Zhou, Hai-Feng Hu, Dian-Wen Ju
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2021-03-01
Series:Pharmaceutical Fronts
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1730956