Asporin stably expressed in the surface layer of mandibular condylar cartilage and augmented in the deeper layer with age

Mandibular condylar cartilage (MCC) exhibits dual roles both articular cartilage and growth center. Of many growth factors, TGF-β has been implicated in the growth of articular cartilage including MCC. Recently, Asporin, decoy to TGF-β, was discovered and it blocks TGF-β signaling. Asporin is expres...

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Bibliographic Details
Main Authors: Yutaka Miyamoto, Hiroyuki Kanzaki, Satoshi Wada, Sari Tsuruoka, Kanako Itohiya, Kenichi Kumagai, Yoshiki Hamada, Yoshiki Nakamura
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187217300207