Immunogenomic determinants of tumor microenvironment correlate with superior survival in high-risk neuroblastoma

Background Tumor-infiltrating CD8+ T cells and neoantigens are predictors of a favorable prognosis and response to immunotherapy with checkpoint inhibitors in many types of adult cancer, but little is known about their role in pediatric malignancies. Here, we analyzed the prognostic strength of T ce...

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Bibliographic Details
Main Authors: Ami V Desai, Stefani Spranger, Thomas F Gajewski, Yuanyuan Zha, Riyue Bao, Jason J Luke, Peter Pytel, Kyle Hernandez, Samuel L Volchenboum, Susan L Cohn
Format: Article
Language:English
Published: BMJ Publishing Group 2021-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/7/e002417.full