A CCR5+ memory subset within HIV-1-infected primary resting CD4+ T cells is permissive for replication-competent, latently infected viruses in vitro

A CCR5+ memory subset within HIV-1-infected primary resting CD4+ T cells is permissive for replication-competent, latently infected viruses in vitro

Abstract Objective Resting CD4+ T cells are major reservoirs of latent HIV-1 infection, and may be formed during the early phase of the infection. Although CCR5-tropic (R5) HIV-1 is highly transmissible during the early phase, newly infected individuals have usually been exposed to a mixture of R5 a...

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Bibliographic Details
Main Authors: Kazutaka Terahara, Ryutaro Iwabuchi, Masahito Hosokawa, Yohei Nishikawa, Haruko Takeyama, Yoshimasa Takahashi, Yasuko Tsunetsugu-Yokota
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Research Notes
Subjects:
HIV
Latent reservoir
Resting CD4+ T cells
Online Access:http://link.springer.com/article/10.1186/s13104-019-4281-5

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http://link.springer.com/article/10.1186/s13104-019-4281-5

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