Developmental signalling in maintenance and regulation of cancer stem cells
Tissue stem cells self-renew throughout the life of an organism thereby maintaining tissue homeostasis and prevent cancer. The major signalling pathways such as Wnt, Notch and Sonic hedgehog control the stem cell regulation and their deregulation leads to cancer. Recent evidences showed that there e...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2015-01-01
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Series: | Biomedical Research Journal |
Subjects: | |
Online Access: | http://www.brjnmims.org/article.asp?issn=2349-3666;year=2015;volume=2;issue=1;spage=37;epage=56;aulast=Dash;type=0 |